1.1 Products name：
Probucol
Chemical name：4，4[（
1-甲基亚乙基）both （sulfur）]
both [2.6-双（1.1-二甲基乙基）phenol
]
or：both （3.5-二丁基羟基苯硫）acetonide
1.2 Chemical structural
formula
1.3 Molecular weight
： 517.86 Molecular
formula：C
31H
48O
2S
2
1.4 Properties：Colourless
crystals or a white
crystalline or granular
powder；Has especially
smelly。Easy to dissolve
in Chloroform, dissolves
in Alcohol, does
not dissolve in
the water 。
2、Quality standard、spec
and packaging requirement
2.1 This product
tallies（Chinese
pharmacopoeia 2005
edition two ）Probucol
under each stipulation
2.2 Packaging and
packing specification：The
outside wrapping
models the compound
bag or the fiber
can for the method
of three-in-one
paper ；
The intension is
two for medicinal
purposes UHMW-PE
membrane bag,25kg/jian。
2.3 Hypolipidemic
。
Summarize
:First does
in US for falls
fat medicine going
on the market, latter
in England, Japan,
Germany and so on
several human of
countries goes on
the market one after
another, after the
clinical practice
discovered Pu spreads
out tests took the
PTCA technique prevents
narrowly applies
drugs again. The
various countries'
expert thought generally
Pu spreads out tests
is one of present
anti-atherosclerosis
effective medicines,
not only Pu spreads
out tests independent
falls the fat medicine,
after its oxidation
resistance, the
anti-inflammation
function, prevents
the PTCA technique
narrow and so on
the aspect curative
effects also very
to be again accurate,
the side effect
is small.In recent
years in our country
heart blood vessel
of brain China level,
in the state-level
magazine has successively
published paper
57 which concerned
Pu spreads out tests,
has enrolled our
country first "Blood
fats Study",
has read in our
country blood vessel
of brain medicine
guide, took independent
kind of oxidation
inhibitor, of has
enrolled technical
college doctor the
teaching material,
is in recent years
one of practicing
physician, pharmacist
examination questions,
has read in the
People's Republic
of China 2005 edition
pharmacopoeias,
in 2004 comments
into the country
medical insurance
table of contents
class B.
Similar
medicine contrast:
Similar medicine
he sandbank class
medicine because
the side effect
big sale market
in the landslide,
on July 21, 2005
the Chinese medicine
newspaper reported,
Canada has called
to his sandbank
class medicine to
stop, the request
production enterprise
changes the instruction
booklet, his sandbank
class medicine only
is falling the blood
fats aspect to spread
out compared to
Pu tests, but in
the oxidation resistance,
the anti-inflammation
and the fatty liver,
familial, homozygote
Gao Dangu aspects
and so on alcoholemia
patient is invalid,
Pu spreads out the
clinical practice
scope which tests
to have his sandbank
class medicine to
be broader than.
